• In silico prediction software SIFT PolyPhen CADD

  2019-06-05

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• As long as developing world health

  2019-06-05

  

  As long as developing-world health systems are ill prepared to offer safe anaesthesia and intensive care to patients in need of surgery, surgically treatable conditions will remain leading causes of death, the world will lose trillions of dollars in gross domestic product, and we in the global healt

• ZIKV is a flavivirus related to dengue

  2019-06-05

  

  ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of la

• buy BIRB796 We did a qualitative analysis to estimate

  2019-06-05

  

  We did a qualitative analysis to estimate the potential risk of Zika buy BIRB796 introduction into the country. We used the circlize statistical package for R software to visualise incoming traffic (logarithm of relative passenger volume) to Pakistani airports from countries characterised as Zika-v

• br Sustained monomorphic ventricular tachycardia br Monomorp

  2019-06-05

  

  Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr

• Currently RFCA is indicated if pharmacologic therapies

  2019-06-05

  

  Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter

• In an early meta analysis diagnosing cancer of the pancreas

  2019-06-05

  

  In an early meta-analysis, diagnosing cancer of the pancreas by ERCP with the “double duct” sign had a sensitivity of 92% and specificity of 96%. In the present case, mild proximal CBD dilatation with an abrupt distal CBD stricture was detected by ERCP. The most common malignant cause of obstructive

• Intimate partner violence is highly prevalent in sub Saharan

  2019-06-01

  

  Intimate partner violence is highly prevalent in sub-Saharan Africa and its role in increasing women\'s risk of HIV acquisition is well recognised, although many aspects of the mechanisms through which HIV increases women\'s risk remain unclear. The most important challenge for researchers is to dev

• El reclutamiento era una tarea

  2019-06-01

  

  El reclutamiento era una tarea permanente de los grupos guerrilleros, en el caso de las mujeres, generalmente mantenían relaciones estrechas con miembros activos de la guerrilla. Hermanos, parientes o amigos sostenían discusiones en el seno familiar sobre las condiciones de injusticia social, repres

• Skin involvement is present in

  2019-06-01

  

  Skin involvement is present in 68–70% of cases of fusariosis [5]. As skin is one of the primary sources of entry, thorough skin examination and biopsy of suspicious nodules should be considered. Sinus involvement occurs in 80% of cases of disseminated fusariosis, with manifestations including facial

• In the univariate subgroup analysis the factors

  2019-06-01

  

  In the univariate subgroup analysis, the factors that predicted reduced survival were increased age, significant mitral regurgitation (≥ grade 2), and creatinine level (Table 4). After multivariate analysis, (+)PES followed by ICD BTL105 was a strong predictor of reduced mortality, along with creati

• topotecan br Reflexiones finales En el proceso armado

  2019-06-01

  

  Reflexiones finales En el proceso armado guatemalteco, diversos acontecimientos otorgaron identidad topotecan las organizaciones revolucionarias y las dotaron de símbolos que cohesionaron la lucha revolucionaria. Tal fue el caso de la Marcha de los claveles rojos, que movilizó a decenas de guatem

• Whole body CT only showed mild splenomegaly cm

  2019-06-01

  

  Whole-body CT only showed mild splenomegaly (14cm) and an enlarged iliac lymph node (1.5×3cm). Cranial MR yielded no specific findings. In the meantime, the patient was given Rituximab. He received 375mg/m2 of Rituximab per week, but after the third dose the patient rapidly developed shock and abdo

• It is well known that the precipitation of solid

  2019-05-31

  

  It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase

• De manera concomitante la confecci n

  2019-05-31

  

  De manera concomitante, la confección de relaciones y crónicas devino una forma de obtener recompensas o beneficios del favor real. De este modo, tanto particulares como miembros de corporaciones (v. gr. la iglesia) elaboraron sus historias (manuscritas o impresas) y buscaron hacerlas llegar al mona

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