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br Materials and methods br Results br
2020-08-05
Materials and methods Results Discussion In 2003, Senegal adopted intermittent preventive treatment for pregnant women (IPTp) using sulfadoxine–pyrimethamine (SP). At the same time, between 2003 and 2004, Senegal switched to sulfadoxine–pyrimethamine with amodiaquine as the first-line thera
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br Introduction The offspring of rodents emit vocalizations
2020-08-05
Introduction The offspring of rodents emit vocalizations when isolated from their dam. The majority of vocalizations by rat pups are in the ultrasonic band frequency of 30–50 kHz (Insel et al., 1986). Maternal separation-induced ultrasonic vocalizations are believed to represent distress signals
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CHIKV belongs to the genus alphavirus which
2020-08-04
CHIKV belongs to the genus alphavirus, which includes other pathogenic viruses like Sindbis virus (SINV), Semliki Forest virus (SFV), Ross River virus (RRV), the western, eastern and Venezuelan equine encephalitis virus (VEEV) etc. These are enveloped, positive-sense ssRNA viruses that are responsib
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ARM1 The results indicated that there were
2020-08-04
The results indicated that there were good agreements between the proposed model predictions and literature experiment data, such that the overall average absolute deviation of gas hydrate formation pressures obtained was lower than 4.2%. Among the studied ionic liquids, the minimum amounts of AADP%
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hippo pathway In summary our present work establishes the ab
2020-08-04
In summary, our present work establishes the ability of the mammalian intestine to function as an environmental sensor able to retain an active metabolic memory for early postnatal nutritional conditions. Epigenetic silencing of the expression of the main cholesterol hippo pathway transporter Npc1l
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br Conclusions The mutation T L present in the Gaba
2020-08-04
Conclusions The mutation T290L present in the Gaba-Cl of dieldrin-resistant R. australis tick strains from Australia is not present in the tick populations from Brazil and Uruguay analysed in this study. Other mutations in the transmembrane 2 domain of Gaba-Cl were detected in fipronil- and linda
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Within the X CX PX RX motif
2020-08-04
Within the X1CX3PX5RX7 motif of several prokaryotic FGE substrates, the residues of X3, X5, and X7 are variably found as mixtures of alanine, glycine, threonine, or serine residues [26], [27]. The docked model of our identified HCTPRRP motif revealed that position X1 (H1) and position X7 (P7) were n
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All eukaryotes possess several E s
2020-08-04
All eukaryotes possess several E2s ranging from about 8 to 11 in certain apicomplexans and Giardia to a little over 50 in certain multicellular plants and animals (Supplementary material). Most of them, barring those in the autophagy pathway (Apg3 and Apg10), are relatively close to each other in se
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Introduction Psoralea corylifolia L Leguminosae is a well kn
2020-08-04
Introduction Psoralea corylifolia L. (Leguminosae) is a well-known traditional Chinese medicine, and it has been widely used for the treatment of various diseases like bronchial asthma, leucopenia, vitiligo and psoriasis in East Asian countries (Zhang et al., 1990). Previous studies have reported t
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br Many dehydrogenases including alcohol dehydrogenase isoci
2020-08-04
Many dehydrogenases, including alcohol dehydrogenase, isocitrate dehydrogenase, and β-hydroxysteroid dehydrogenase, can be inhibited by their own substrate, particularly at elevated substrate concentrations [112]. This substrate inhibition phenomenon was also observed for the Δ1-KSTDs from C. test
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br Material and methods br Results br Discussion
2020-08-03
Material and methods Results Discussion We previously reported that type I collagen is a potent inducer of linear invadosomes (Juin et al., 2012) and that DDR1 is required for their formation and matrix degradation activity (Juin et al., 2014) (Di Martino et al., 2015). As TGF-β1 was descri
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br Introduction P Y receptors are membrane
2020-08-03
Introduction P2Y receptors are membrane bound and G-protein-coupled receptors (GPCRs) for extracellular nucleotides (Burnstock and Kennedy, 1985). Eight mammalian P2Y receptor subtypes (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and P2Y14) have been identified (Ralevic and Burnstock, 1998; von
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Although it is believed that CYP induction
2020-08-03
Although it is believed that CYP induction is regulated in humans in principle in the same fashion as in animals, some species differences in CYP3A STAT5 Inhibitor induction were observed. Rifampicin is known to be a potent inducer of CYP3A4 in human hepatocytes, whereas pregnenolone-16α-carbonitri
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In rats exposed to days of nicotine treatment
2020-08-03
In rats exposed to 7 days of nicotine treatment (12 h after the last nicotine administration) we observed increases in horizontal and vertical locomotor activity along with increases in the dorsal and ventral striatal dopamine release. This finding is in line with previous studies which reported loc
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The ASD associated mutations fall outside the CPG
2020-08-03
The ASD associated mutations fall outside the CPG2 region that we mapped in this study. While they are close enough (exon 9 and exon 60) that we initially considered the possibility that they would be contained within a human CPG2 transcript longer than the rat homolog, our data suggest that other a
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